![]() Since then, he was followed by the “London patient,” Adam Castillejo, and “the Düsseldorf patient,” whose identity has not been revealed. He would die in 2020 when his leukemia returned. Over a decade ago, Timothy Ray Brown, or “ the Berlin patient” was the first person to essentially be cured of HIV by way of stem cell transplants. Why this case is a breakthrough in HIV treatment “Just as these three men provide hope for those living with HIV, so does our case, and especially for women.” Women represent approximately 50% of people living with HIV globally,” Persaud told Healthline. “This individual is the first woman to be in remission following stem cell transplant for blood cancer. Deborah Persaud, co-lead study author and the interim director of Pediatric Infectious Diseases, and a professor of pediatrics at Johns Hopkins University School of Medicine, said this point is especially important. Given that this is the first woman of color who has achieved HIV remission, experts say it also underscores why more needs to be done to include people from underrepresented communities in studies, clinical trials, and cutting-edge research.ĭr. This case study underscores our growing understanding of how modern medicine is tackling an enduring global health crisis – 38.4 million people are living with HIV worldwide, according to current data from the World Health Organization (WHO). Their stem cell transplants came from compatible adult donors, while hers were derived from cord blood. She follows three others (all men), who have seen their HIV effectively be “cured” as a result of stem cell transplants. They paint a full picture of the so-called “New York patient,” a middle-aged woman who self-identifies as mixed race and has now been living with her HIV in remission since 2017. Now a year later, the researchers are sharing their full findings in the journal Cell. Researchers at the 29th annual Conference on Retroviruses and Opportunistic Infections announced in 2022 that the fourth person was effectively “cured” of HIV by way of stem cell transplants for blood cancer, in this case, acute myeloid leukemia (AML). Previous procedures used stem cell transplants that came from compatible adult donors.The stem cell transplants for her procedure were the first to be derived from cord blood.She is currently one of only four people whose HIV reached a state of remission after receiving stem cell transplants.The full findings from a case study on the first woman to be effectively “cured” of HIV have been released by researchers.Doctors then transplant stem cells from individuals with a specific genetic mutation in which they lack receptors used by the virus to infect cells.Share on Pinterest Stem cell transplants derived from umbilical cord blood were used to effectively ‘cure’ a woman of HIV for the first time. Patients in the trial first undergo chemotherapy to kill off the cancerous immune cells. It aims to follow 25 people with HIV who undergo a transplant with stem cells taken from umbilical cord blood for the treatment of cancer and other serious conditions. Deborah Persaud of Johns Hopkins University in Baltimore. Yvonne Bryson of the University of California Los Angeles (UCLA), and Dr. The case is part of a larger U.S.-backed study led by Dr. "This is now the third report of a cure in this setting, and the first in a woman living with HIV," Sharon Lewin, President-Elect of the International AIDS Society, said in a statement. The two prior cases occurred in males - one white and one Latino - who had received adult stem cells, which are more frequently used in bone marrow transplants. Since receiving the cord blood to treat her acute myeloid leukemia - a cancer that starts in blood-forming cells in the bone marrow - the woman has been in remission and free of the virus for 14 months, without the need for potent HIV treatments known as antiretroviral therapy. The case of a middle-aged woman of mixed race, presented at the Conference on Retroviruses and Opportunisitic Infections in Denver, is also the first involving umbilical cord blood, a newer approach that may make the treatment available to more people. patient with leukemia has become the first woman and the third person to date to be cured of HIV after receiving a stem cell transplant from a donor who was naturally resistant to the virus that causes AIDS, researchers reported on Tuesday. ![]()
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